Zallouh root - Ferula hermonis

 Zallouh is made from the dried root of the herb Ferula Hermonis which grows at a height of about 2000 meters above sea level on the side of Mount Hermoun between Lebanon and Syria. Zallouh has been used historically in the region as an aphrodisiac, but it has only been in the past few years that scientists have evaluated it's chemical properties. Zallouh contains a number of compounds, including sesquiterpenes. 

What's in Zallouh herb?
Zallouh extract contains ferutinin, teferin and teferdin.

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Zallouh Research
An intriguing study in male rats showed that zallouh, when given one time, enhanced sexual activity, and also raised blood levels of testosterone. However, when zallouh was given daily for 10 days, it actually reduced sexual activity, and also reduced testosterone levels.

The crude oil from zallouh can enhance erectile function in rodents, however zallouh becomes toxic if used for a long period of time in high doses.

In mice, the ingestion of 3 mg/kg of aqueous extract of zallouh for six weeks inhibited social aggression. Body weight and other sex accessory organ weights were significantly reduced. The ingestion of high doses of zallouh by male mice resulted in a significant reduction of their fertility.

Summary
At this point it is difficult to make any firm recommendations regarding the use of zallouh. Occasional use appears to be safe, but long term use is discouraged until more is known whether or not zallouh is toxic with chronic use.

Zallouh Research Update
Ferula hermonis impairs sexual behavior in hormone-primed female rats.
Physiol Behav. 2005 Sep 15;86(1-2):69-74. Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Italy.
The influence of Ferula hermonis root extract Zallouh on sexual behavior was studied in female rats. Sexual receptivity, proceptivity and paced mating behavior were evaluated in ovariectomized females primed with estradiol benzoate (EB) and progesterone (P) and then treated with zallouh extract acutely (30 and 60 mg/kg) or subchronically (1 and 10 mg/kg daily for 10 consecutive days). A significant reduction in lordosis responses was observed in rats after acute (60 mg/kg) or subchronic (1 and 10 mg/kg) administration of the plant extract. Similarly, a decrease in proceptive behaviors was exhibited by zallouh treated rats in comparison with EB+P controls. No difference was found in the patterns of paced mating behavior between control and treated animals. The present results demonstrate that the acute or repeated ingestion of Ferula hermonis specifically impairs the receptive and proceptive components of female sexual behavior. The effect could be the consequence of an antiestrogenic action of the extract in hormone-primed female rats.
   Comments: sometimes too high a dose of an herb has the opposite effect or an unexpected effect. Furthermore, when used occasionally and herb may have positive sexual effects which can be reversed with chronic use.

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