Tyrosine pill
Tyrosine and thyroid research

Tyrosine is not an essential amino acid since tyrosine can be made from the amino acid phenylalanine. Tyrosine can be converted into dopamine and norepinephrine. Supplementation with both tyrosine and phenylalanine leads to alertness and arousal.

Tyrosine 750 mg, Club Natural
L Tyrosine Supplement Facts
L Tyrosine - 750 mg

If you plan to take tyrosine, limit your dose initially to a third or half a capsule until you find out how tyrosine reacts in your system.
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Phenylalanine and tyrosine are sometimes prescribed as antidepressants, usually in combination with other nutrients and herbs that have mood elevating properties. Some doctors also recommend these amino acids for appetite control. Phenylalanine may trigger the release of an appetite-suppressing hormone in the gut called cholecystokinin. Most individuals who take either of these amino acids notice improved alertness, arousal, and mood, and slight loss in appetite. I have a few patients who occasionally take a small amount of these nutrients, such as 50 to 250 mg, in the morning as a substitute for caffeine. Also consider Tyrosine-N-Acetyl.

Tyrosine and thyroid
We get a lot of questions from people asking if tyrosine can be used instead of thyroid medication such as Synthroid. Tyrosine is an amino acid that cannot take the role of thyroid medication. We also don't recommend using a high dose of tyrosine with thyroid medications since heart rhythm problems may occur.

Tyrosine Emails
Q. I continue to learn from Mind-Boosters book. It is the one source that I continually return to when exploring nutritional approaches. My question concerns Tyrosine. I have recently begun taking Acetyl L-Tyrosine, one 300 mg. tablet in the morning. It seems to increase energy, and even give a little boost in the area of verbal fluency (an area that I am very interested in improving). I seem to "feel like talking" more than I normally would, and the words seem to come a little more easily. However...I'm having a lot of trouble sleeping, even with this small (I think) dosage, I seem to have a "wired" feeling. I would hate to give up the benefits of tyrosine.
   A. 300 mg of acetyl-tyrosine is actually, in our opinion, a high dose. Acetyl-tyrosine is probably much more active that tyrosine by itself. The alertness it produces does cause insomnia. A lower dosage may reduce the side effects.

Q. I have read alot on the site about the cautions of 5-HTP and would like to ask about whether there are
any risks of using L-Tyrosine in the long-term. For me, this supplement really helps with my mood but I
would like to know whether the amino acid is safe for daily consumption at a high dose(12 grams). I do not
experiences any side-effects from this amino acid and have not read any reports of toxicity ever occurring
from its use.
   A. Twelve grams of tyrosine is a very high dose. Side effects could include irritability, anxiety,  heart irregularities and perhaps  over the long run could have a pro oxidant effect on certain brain cells, but this is just my hypothesis. Tyrosine seems to be more effective in those whose depression is due to low dopamine levels. It's probably best to not use one particular nutrient to treat depression for prolonged periods but to alternate different ones such as St. John's wort, SAMe, 5-HTP, etc.

Q. I have mild depression and depersonalisation and had to start St Johns wort which caused me a lot of arrythmias and feelings of mania, restlessness-at least now the symptoms are gone. I had to cut them down and my depression got much worse but now I am thinking to get some l-tyrosine-would you say 250 mg could possibly help me? I am also taking 500 mg l-lysine which calms me down. Do you think their combo is a bad idea?
   A. We can't predict any person's response to supplements. L Tyrosine may help some people with depression, but there are other supplements that could also help such as SAM-e and 5-HTP. It is important to use low dosages since these supplements can have side effects when taken in high dosages. We are not aware of any bad interaction between lysine and tyrosine supplements.

Q. I have a question about l-tyrosine. There is a tanning pill called pro tan e-z caplets with 1000mg of l-tyrosine in them. Could you tell me (before I decide to make my purchase of them) if this is a safe dose? It says it is ephreda free also. I would like a professional opinion before my l tyrosine purchase. That way I can decide if pro tan e-z caplets is a good purchase as a tanning pill.
   A. L-tyrosine, in dosage greater than 300 or 500 mg, may, in some people, cause heart rhythm problems, anxiety, and restlessness. We have not seen any evidence that taking a tyrosine supplement helps with tanning. You may wish to ask the company selling this product to show scientific papers that their product enhances tanning and does so safely.

Tyrosine kinase inhibitor
PKC412, a small-molecule tyrosine kinase inhibitor, in early studies in 2007, is showing encouraging results as a single compound therapy for pancreatic cancer.

Q. Antidepressants have induced anhedonia. Should I take tyrosine?
   A. See the page on depression for ideas. We can't advice whether you should or should not take tyrosine or any supplement.

Q. I suffer from severe M.E. and have a border line thyroid function test and low DHEA. I felt better at first on the natural thyroid Westhroid which my doctor prescribed but then started with palpitations and pain at the back of my neck at night and some strange sensations in my chest. I heard about Thyrosine and after surfing the web read many sites talking about thyrosine and tyrosine. My question to you is are these two substances the same thing? I want to know if Thyrosine and tyrosine are one and the same first.
   A. We had not heard of thyrosine before, but a search on the internet shows it is the name of a product that has many different ingredients. Therefore, Thyrosine and tyrosine are not the same thing.

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