Slentrol obesity drug for dogs

Slentrol is manufactured by Pfizer Inc., New York, N.Y. If you have an interest in learning about natural ways to treat obesity, see weight loss.

Philosophical comments regarding Slentrol
One wonders what kind of country the USA has become when we have such excess resources to devote to creating a drug for obesity treatment in a dog when there are starving people within the USA and all over the world. No wonder many people in poor foreign countries have such a negative attitude about America.

FDA Approves the First Drug for Obese Dogs
January 2007 - The Food and Drug Administration has approved Slentrol (dirlotapide), a prescription pharmaceutical drug for the management of obesity in dogs. Slentrol reduces appetite and fat absorption to produce weight loss. A veterinarian will determine whether the dog should be treated, based on the dog's weight and general health. "This is a welcome addition to animal therapies, because dog obesity appears to be increasing," said Stephen Sundlof, D.V.M., Ph.D., director of FDA's Center for Veterinary Medicine. "Veterinarians are well aware that overweight pets are at a higher risk of developing various health problems, from cardiovascular conditions to diabetes to joint problems." Veterinarians generally define a dog that weighs 20 percent more than its ideal weight as obese. Surveys have found that approximately 5 percent of dogs in the United States are obese, and another 20-30 percent are overweight. Slentrol is a new chemical entity, called a selective microsomal triglyceride transfer protein inhibitor, which blocks the assembly and release of lipoproteins into the bloodstream. The mechanism for producing weight loss is not completely understood, but seems to result from reduced fat absorption and a satiety signal from lipid-filled cells lining the intestine. Slentrol is given to the dog in varying amounts over the course of the treatment. The dog is given an initial dose for the first 14 days. After that, the veterinarian will assess the dog's progress at monthly intervals, adjusting the dose depending on the dog's weight loss. After the dog has achieved the goal weight, the drug's manufacturer recommends continued use of the drug during a three-month period, while the veterinarian and dog owner establish the optimal level of food intake and physical activity needed to maintain the dog's weight.

Slentrol side effects
Slentrol side effects include vomiting, loose stools, diarrhea, lethargy and loss of appetite. Side effects of Slentrol with human use may lead to abdominal distention, abdominal pain, diarrhea, flatulence, headache, nausea and vomiting.

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