Rhodiola and mood - Does this herb help with depression? Anti-depressant benefit

Rhodiola rosea, also known as golden root,  grows in the Arctic regions of eastern Siberia.  Rhodiola is a popular plant in traditional medical systems in Eastern Europe and Asia. Russians have drunk rhodiola tea for centuries as an energy booster. Russian and Chinese scientists have researched the benefits of rhodiola rosea for several decades. Claims are made that rhodiola rosea that increase an organism's resistance to stress. It has been proposed that rhodiola rosea plant can extend longevity and improve health span by reducing oxidative stress.

Rhodiola Rosea Extract, Full Spectrum, 327 mg, 60 Tablets - Planetary Formulas

Full Spectrum Rhodiola rosea root combines an extract standardized to 0.8% rosavin with whole rhodiola root extract, providing a broad spectrum of rhodiola constituents.

Rhodiola rosea root is a legendary adaptogenic tonifier that comes from the polar arctic regions of Eastern Siberia. Among traditional people it is highly valued as a strengthening tonic to increase physical and mental stamina.


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Supplement
Rhodiola root extract (standardized to 0.8% salidrosides and 0.8% rosavins)      
Rhodiola rosea root extract 4:1      

Suggested Use:  One rhodiola tablet a few days a week, preferably in the morning a few minutes before breakfast.

* Rhodiola Rosea root extract daily value not established.

Rhodiola species
Dozens of species of Rhodiola grow wild in nature. Rhodiola has a reputation for stimulating the nervous system, decreasing depression, enhancing work performance, eliminating fatigue, and preventing high altitude sickness. Rhodiola rosea has been categorized as an adaptogen by Russian researchers due to its observed ability to increase resistance to a variety of chemical, biological, and physical stressors. The adaptogenic, cardiopulmonary protective, and central nervous system activities of Rhodiola rosea have been attributed primarily to its ability to influence levels and activity of monoamines and opioid peptides such as beta-endorphins. It is not known at this time whether Rhodiola influences sexual activity. For more rhodiola information.


Benefit of rhodiola rosea herb

Antiaging properties of rhodiola rosea
Rhodiola: A Promising Anti-Aging Chinese Herb.
Rejuvenation Res. 2007 Nov 8; Jafari M, Felgner JS, Bussel II, Hutchili T, Khodayari B, Rose MR, Mueller LD. Department of Pharmaceutical Sciences, University of California, Irvine, California.
Using the fruit fly, Drosophila melanogaster, we investigated the effects of Rhodiola on life-span. Rhodiola supplied every other day at 30 mg/mL significantly increased the lifespan of Drosophila melanogaster. When comparing the distribution of deaths between Rhodiola-supplemented and control flies, Rhodiola-fed flies exhibited decelerated aging.

Anti-inflammatory activity of rhodiola herb
Anti-inflammatory activity of Rhodiola rosea - "a second-generation adaptogen"
Phytother Res. 2009 Jan 16. Pooja, Bawa AS, Khanum F. Defence Food Research Laboratory, Sidddarthanagar, Mysore-570011, Karnataka, India.
Rhodiola rosea (golden root), a unique phytoadaptogen grown in high-altitude regions has gained attention for its various therapeutic properties. In India, this plant is found in the Himalayan belt and has not been completely explored for its beneficial health effects. The present study was undertaken to evaluate the anti-inflammatory efficacy of the tincture extract of Rhodiola rosea roots. Our results showed a potent inhibition against Cox-2 and PLA(2). Inhibition of nystatin induced oedema and phospholipase A(2) suggested that membrane stabilization could be the most probable mechanism of action of rhodiola root extract in anti-inflammation. The findings in this study may provide the use of rhodiola rosea root extract in the treatment of inflammatory conditions.

Antioxidant and Organ Protection
Rhodiola therapy may protect hypoxia-induced pancreatic injury in two ways. It prevents hypoxia-induced biological changes by increasing intracellular oxygen diffusion and efficiency of oxygen utilization. Alternatively, it reduces hypoxia-induced oxidative damage by its antioxidant activities.

Rhodiola antidepressant
Some people claim rhodiola rosea is an antidepressant. Rhodiola does have some mood lifting ability but it is not as effective an antidepressant as 5HTP and SAM-e.

Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression.
Nord J Psychiatry. 2007;61(5):343-8. Darbinyan V, Aslanyan G, Amroyan E, Gabrielyan E, Malmström C, Panossian A.
Department of Neurology, Armenian State Medical University, Yerevan, Armenia.
The objective of this study was to assess the efficacy and safety of standardized extract SHR-5 of rhizomes of Rhodiola rosea L. in patients suffering from a current episode of mild or moderate depression. Patients with initial Hamilton Rating Scale for Depression scores between 21 and 31 were randomized into three groups, one of which (group A: 31 patients) received two tablets daily of SHR-5 (340 mg/day), a second (group B: 29 patients) received two tablets twice per day of SHR-5 (680 mg/day), and a third (group C: 29 patients) received two placebo tablets daily. The efficacy of rhodiola roseas extract with respect to depressive complaints was assessed on days 0 and 42 of the study period from total and specific subgroup HAMD scores. For individuals in groups A and B, overall depression, together with insomnia, emotional instability and somatization, but not self-esteem, improved significantly following medication, whilst the placebo group did not show such improvements. No serious side-effects were reported. It is concluded that the standardized rhodiola rosea extract shows anti-depressive potency in patients with mild to moderate depression when administered in dosages of either 340 or 680 mg/day over a 6-week period.

Memory and Learning
Studies with mice did not show rhodiola to have much of an effect on memory.

Stress and Fatigue
Rhodiola may be helpful in increasing energy and decreasing mental fatigue. The objective was to investigate the stimulating and normalizing effect of the adaptogen Rhodiola rosea extract SHR-5 in foreign students during a stressful examination period. The study was performed as a double-blind, randomized and placebo-controlled with low repeated dose regime. The study drug and the placebo were taken for 20 days by the students during an examination period. The physical and mental performance were assessed before and after the period, based on objective as well as on subjective evaluation. The most significant improvement in the SHR-5 group was seen in physical fitness, mental fatigue and neuro-motoric tests (p <0.01). The self-assessment of the general well-being was also significantly (p < 0.05) better in the verum group. No significance was seen in the correction of text tests or a neuro-muscular tapping test. The overall conclusion is that the study drug gave significant results compared to the placebo group but that the dose level probably was suboptimal.

This was another study with doctors working night shift in a hospital. The aim of this study was to investigate the effect of repeated low-dose treatment with a standardized extract SHR/5 of rhizome Rhodiola rosea L, (RRE) on fatigue during night duty among a group of 56 young, healthy physicians. The effect was measured as total mental performance calculated as Fatigue Index. The tests chosen reflect an overall level of mental fatigue, involving complex perceptive and cognitive cerebral functions, such as associative thinking, short-term memory, calculation and ability of concentration, and speed of audio-visual perception. These parameters were tested before and after night duty during three periods of two weeks each: a) a test period of one RRE/placebo tablet daily, b) a washout period and c) a third period of one placebo/RRE tablet daily, in a double-blind cross-over trial. The perceptive and cognitive cerebral functions mentioned above were investigated using 5 different tests. A statistically significant improvement in these tests was observed in the treatment group (RRE) during the first two weeks period. No side-effects were reported for either treatment noted. These results suggest that RRE can reduce general fatigue under certain stressful conditions.

A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue.
Planta Med. 2009 Feb;75(2):105-12. Olsson EM, von Schéele B, Panossian AG. Department of Psychology, Uppsala University, Uppsala, Sweden.
The aim of the study was to assess the efficacy of the standardised extract SHR-5 of roots of Rhodiola Rosea L. in the treatment of individuals suffering from stress-related fatigue. A total of 60 individuals were randomised into two groups, one of which received four tablets daily of SHR-5 extract (576 mg extract/day), while a second received four placebo tablets daily. Repeated administration of R. ROSEA extract SHR-5 exerts an anti-fatigue effect that increases mental performance, particularly the ability to concentrate, and decreases cortisol response to awakening stress in burnout patients with fatigue syndrome.

What's in Rhodiola?
There are dozens of substances in Rhodiola and it is difficult to say which are the active ingredients. The dried rhizomes contain 0.05% essential oil with the main chemical classes: monoterpene hydrocarbons (25.40%), monoterpene alcohols (23.61%) and straight chain aliphatic alcohols (37.54%). n-Decanol (30.38%), geraniol (12.49%) and 1,4-p-menthadien-7-ol (5.10%) were the most abundant volatiles detected in the essential oil, and a total of 86 compounds were identified. Geraniol was identified as the most important rose-like odour compound besides geranyl formate, geranyl acetate, benzyl alcohol and phenylethyl alcohol. Floral notes such as linalool and its oxides, nonanal, decanal, nerol and cinnamyl alcohol highlight the flowery scent of rose root rhizomes.
    Additional molecules include rosavin, rosin, and rosarin, salidroside and lotaustralin.

Rhodiola and stamina
Rhodiola rosea, also known as golden or Arctic root, grows in the Arctic regions of eastern Siberia. Rhodiola is a popular plant in traditional medical systems in Eastern Europe and Asia. Russians have drunk rhodiola tea for centuries as an energy booster. The purpose of this study conducted at Katholieke Universiteit Leuven in Belgium. was to investigate the effect of acute and long term 4-week Rhodiola rosea intake on physical capacity, muscle strength, and reaction time. During the acute phase of the study, subjects were given 200-mg of Rhodiola rosea extract and the results compared a few days later when they were given placebo pills. Subjects given rhodiola had slightly more stamina. The time to exhaustion during exercise was 17.2 minutes compared to 16.8 min on placebo. Also, lung ventilation capacity improved during rhodiola treatment. In a second phase of the study, subjects subjects ingested 200 mg of rhodiola for 4 weeks. The results showed that there was no difference in stamina when compared to placebo.
   Comments: It appears that Rhodiola rosea intake for a day or two can improve endurance exercise capacity, but long term use does not make much of a difference.


Availability of rhodiola
Rhodiola is sold in capsule, tablet, and tea form. Dosage ranges from 100 to 400 mg a day. Rhodiola rosea herb or extract is also added to many different herbal formulas.


Rhodiola plant emails
Q. What is New Chapter rhodiola?
   A. New Chapter rhodiola product contains: Rhodiola (Rhodiola rosea), (root), hydroethanolic extract (5.4-6.6% total rosavins, including 3.6-4.4% rosavin and 0.9-1.1% salidrosides).

Q. Does rhodiola rosea help with female impotence?
   A. Rhodiola rosea plant has some sexual enhancing benefits, but there are other herbs that are more potent.

Q. i am looking for a caffeine alternative to help with energy during the day and for better mental clarity while studying. Is rhodiola good for this purpose?
   A. Mind Power Rx is great for mental clarity, focus and alertness. MultiVit Rx is great for overall physical and mental energy and vitality. Most people prefer these combination formulas to the single herbs such as rhodiola or ashwagandha, but rhodiola does help many people with energy and alertness.


Rhodiola suppliers
Jiahe Phytochem Co., Ltd. A source of Rhodiola Rosea extract  The Following Specifications Available  Salidroside 1%-3%, Rosavin 1%- 3%, Rosavins 1%- 5%, Salidroside 1%-3% plus Rosavin 1%- 3% . Rhodiola rosea ("golden root" or "Arctic root") is widely distributed at high altitudes in Arctic and mountainous regions throughout Europe and Asia. It is a popular plant in traditional medical systems in Eastern Europe and Asia. Current studies supporting Rhodiola Rosea has benefits of stimulating the nervous system, decreasing depression, enhancing work performance, eliminating fatigue, and preventing high altitude sickness. Adaptogenic, Anti-Stress, Endocrine and Reproductive Effects Cardioprotective Effects. SHAANXI JIAHE PHYTOCHEM CO.,LTD
Xi'an High-tech Development Zone,Shaanxi 710075, China

We supply genuine Russian dry cut roots of Rhodiola Rosea. We could supply Rhodiola Rosea in large quantities as well,  from several kilos to several tons. In case of big order the discount is possible. Rhodiola rosea is of Russian origin (Altai Mountains, Siberia, Russia). Rhodiola Rosea has extraordinary pharmacological properties as adaptogene, an anti-mutagen and anti-depressive. Yours sincerely, Irina Sushko, Product manager, Adriatic Herbals Inc.

Qinghai lake Medicine CO. ltd of Qinghai Province is a medium-sized comprehensive pharmaceutical enterprise can provide lots of Rhodiola Rosea Extract.

Rhodiola supplement questions
Q. Can a rhodiola supplement help me sleep?
   A. In most people, rhodiola herb has an energizing effect and high dosages could lead to insomnia.

I am a 62 yo male general health good, 5'9" 190lbs, except i do suffer from extreme fatigue, and moderate depression, this has been going on for years!, and after three different doctors, i decided to try rhodiola rosea, for increased energy, and sense o well being. I will be taking 250 mg of 3% rosavines, 1% salidrosides. Is one cap a day enough? also i take med for high blood presser, would it hurt to take rhodiola roseea? And lastly, do you think this will help my situation? I am so tired of waking up every day feeling bad, with no energy, or desire to do anything.
    It is not possible for us to know how or whether this supplement will help you. There are many causes for fatigue and depression.

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