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Reishi and viruses
Reishi has compounds that may have antiviral activity, including activity against the Epstein-Barr virus.
Reishi and immune function
Oral administration of reishi results in Th1-associated immuno-potentiating activities in vivo.
Additional benefits of Reishi
Animal studies indicate reishi has the ability to lower cholesterol levels.
Giving reishi to human volunteers for a period of 4 weeks did not lead to any toxicity.
Reishi inhibits aldose reductase
The inhibitory effect on aldose reductase by an extract of Ganoderma lucidum Reishi.
Phytother Res. 2009 Jan; Department of Forest and Forest Product Sciences, Faculty of Agriculture, Kyushu University, Fukuoka 812-8581, Japan.
The human aldose reductase inhibitory effects of the methanol extracts of 17 medicinal and edible mushrooms were examined. Ganoderma lucidum showed the highest aldose reductase inhibitory activity compared with the other mushrooms. The effect of an ethanol extract of reishi mushroom on the galactitol level in the eye lens was studied in a galactosemic rat model in vivo. This mushroom significantly decreased the galactitol accumulation.
Reishi Research Update
Ganoderma lucidum (Reishi) inhibits proliferation and induces apoptosis in human prostate cancer cells PC-3.
Jiang J,. Methodist Research Institute, E504, Indianapolis, IN .
Int J Oncol. 2004 May;24(5):1093-9.
Ganoderma lucidum (Reishi), an oriental medical mushroom, has been widely used in Asian countries for centuries to prevent or treat different diseases, including cancer. However, the mechanism(s) responsible for the effects of reishi on cancer cells remain to be elucidated. We have previously demonstrated that reishi down-regulated the expression of NF-kappaB-regulated urokinase plasminogen activator (uPA) and uPA receptor (uPAR), which resulted in suppression of cell migration of highly invasive human breast and prostate cancer cells. In this study, we investigated the effects of reishi on cell proliferation, cell cycle, and apoptosis in human prostate cancer cells PC-3. Our data demonstrate that reishi inhibits cell proliferation in a dose- and time-dependent manner by the down-regulation of expression of cyclin B and Cdc2 and by the up-regulation of p21 expression. The inhibition of cell growth was also demonstrated by cell cycle arrest at G2/M phase. Furthermore, reishi induced apoptosis of PC-3 cells with a slight decrease in the expression of NF-kappaB-regulated Bcl-2 and Bcl-xl. However, the expression of proapoptotic Bax protein was markedly up-regulated, resulting in the enhancement of the ratio of Bax/Bcl-2 and Bax/Bcl-xl. Thus, reishi exerts its effect on cancer cells by multiple mechanisms and may have potential therapeutic use for the prevention and treatment of cancer.
Reishi mushroom supplement emails
Q. I received three bottles of reishi mushroom this week. There is 100 mg of Calcium with 920 mg of reishi mushroom. How does calcium work with reishi? If Calcium is abundant in the blood stream and already there is formation of plaque by cholesterol and fatty acid, fit is very likely calcium will adhere to the sticky cholesterol. repeating its process over and over until the artery is totally blocked. I am 62 years old female. In the last month I discover that I
am pre-hypertensive and sensitive to salt intake. Would reishi with calcium affect my condition negatively? I know the benefit or reishi and I have taken them on and off (brew in the Chinese way). Shells are added to the pot of reishi plus
other herbs, I believe the shells contain calcium. How long does one need to take reishi?
A. Planetary Formulas routinely adds calcium to some of their capsules or tablets for a number of herbs as part of the production process. We don't think calcium has any significant influence on the function of reishi mushroom supplement. Only when calcium ingestion through supplements reaches more than 600 to 800 mg daily for many years should one be concerned with any possibility of plaque formation. We don't know how reishi with calcium influences blood pressure. Reishi is taken as needed. The length of time or dosage depends on the medical reasons one is taking and that is up to you and your health care provider. It is a good idea to take breaks from use of herbs and mushrooms but we can't be any more specific since each person is different.
Q. Is the Reishi by Planetary Formulas same as
A. The reishi by Planetary Formulas is a different brand than ReishiMax made by Pharmanex. There have not been any studies comparing the two brands therefore it is not possible to say whether one reishi brand is better or worse than the other brand.
Q. I am interested in acquiring either a tincture
or tea of the Reishi mushroom. I have heard that the "Red Reishi" mushroom
is very powerful. I am dealing with colorectal stage 4 cancer, metastases
to the liver, so we are looking to maintain a good quality of life for
however much time remains. We've found encouraging research data on the
Reishi Mushrooms and would like to add them in one form or another to our
A. You may google reishi mushroom tea or tincture to find a store that sells them. We wish you well. See colon cancer for info on natural colon cancer treatment or prevention studies.
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We will update this page with more reishi research
as they are published. The benefits of reishi mushroom are varied and
further investigations will reveal the full potential of this