Cetyl myristoleate (CMO) is the common name for cis-9-cetyl myristoleate,
a compound synthesized from cetyl alcohol and mysristoleic acid. The
rational for the use of CMO is that it may inhibit the production of
inflammatory prostaglandins and leukotrienes.
CMO was discovered in 1972 by Harry W. Diehl, Ph.D., a
researcher at the National Institutes of Health. At the time, Dr. Diehl
was responsible for testing anti-inflammatory drugs on lab animals. In
order for him to test the drugs, he first had to artificially induce
arthritis in the animals by injecting a heat-killed bacterium called
Freund’s adjuvant. Dr. Diehl discovered that Swiss albino mice did not get
arthritis after injection of Freund’s adjuvant. Eventually, he was able to
determine that cetyl myristoleate CMO was the factor present naturally in
mice that was responsible for this protection. When CMO was injected into
various strains of rats, it offered the same protection against arthritis.
It has been proposed that CMO acts as a joint “lubricant” and
anti-inflammatory agent. For more
CMO information.
CMO product and Joint Power Rx with CMO

Cetyl
Myristoleate
Fatty Acid Complex for Joints, from beef tallow
CMO contains concentrated extract of the
fatty acid cerasomal-cis-9-acetyl-myristoleate from natural bovine source. CMO is not found in any vegetable oils or other common foods. CMO is
found in low amounts in animal connective tissue.
CMO contains the identical compound referenced in published clinical trials.
Usage: Take 1 CMO capsule daily in the morning, or as directed by your
qualified health consultant.
CMO Supplement Facts
CMO -
Cetyl Myristoleate Extract - 400 mg
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CMO and Osteoarthritis
Cetylated fatty acids improve knee function in patients with
osteoarthritis.
CMO questions
Q. I am Interested in the
CMO product by Physician Formulas. It recommends on the
label 1 tablet a day. Many of
the other cmo products on the market recommend about 6 tablets a day. I
want the product to work. Is more better, or just a waste? recently diagnosed
with rheumatoid arthritis.
A. Since hardly any human studies have been done with CMO, there is
no clear understanding of the dosage required for optimal benefit. Hence, it is
a good and safe idea to start with one capsule of CMO and gradually increase
over days and weeks with medical supervision until an amount is reached that
provides a satisfactory response.
Q. What is the amount of CMO in the CMO 400 mg complex
capsule? Is it 40% which is 160 mg pure CMO? What is the amount of CMO in the
Joint Power Rx capsule? Is the 100 mg pure CMO, or is it the CMO complex?
A. Cetyl Myristoleate complex - 400 mg (Fatty acid complex with
cetyl myristoleate at 40 percent, along with several other fatty acids including
cetyl myristate, cetyl palmitate, cetyl laurate, cetyl palmitoleate, and cetyl
oleate). So it is 160 mg CMO per 400 mg of CMO complex. In the Joint Power Rx,
it is 100 mg of CMO complex which is 40 mg of CMO.
Q. Has the source of beef tallow been tested free of
mad cow disease?
A. Mad cow disease comes from brain tissue of cows, not from their
body fat.
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