Carnosine pill
for autism, side effects, for heart and anti-aging
Carnosine is a small molecule composed of the amino acids histidine and alanine.
Carnosine is found in relatively high concentrations in several body tissues—most
notably in skeletal muscle, heart muscle, nerve tissue and brain. The exact biological
role of carnosine is not well understood, but many studies indicate that carnosine has
antioxidant potential. Carnosine may also act as a neurotransmitter (chemical messenger in
the nervous system). Carnosine generates nitric oxide better than arginine. Nitric oxide
helps dilate blood vessels.
L Carnosine
supplement
L-Carnosine is a dipeptide composed of the covalently bonded amino
acids alanine and histidine and is found in the brain, heart, skin,
muscles, kidneys and stomach. L-Carnosine is naturally produced in the
body by the enzyme carnosine synthetase.
L-Carnosine supports healthy aging and cellular rejuvenation by its
effects on two mechanisms: Glycosylation and Free Radical Damage.
Glycosylation is the oxidation of proteins by glucose resulting in
cross-linking of proteins and which is implicated in loss of cell
function, genome integrity and accelerated aging.
L Carnosine also protects the aging process of the brain by retarding
lipid peroxidation and stabilizing cell membranes.
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Carnosine Studies Show:
L-Carnosine is a dipeptide composed of the covalently bonded amino
acids alanine and histidine and is found in the brain, heart, skin,
muscles, kidneys and stomach. L-Carnosine is naturally produced in the
body by the enzyme carnosine synthetase. The exact role of carnosine supplementation in
human health is not clear at this time but carnosine appears to be a promising nutrient
with much potential.
Carnosine may be helpful in children with autism.
The dose would be much less than in adults.
Topical N-Acetyl-carnosine eyedrops shows potential for the treatment and prevention of
cataracts.
Carnosine and aging
L-Carnosine supports healthy aging and cellular rejuvenation by its
effects on two mechanisms: Glycosylation and Free Radical Damage.
Glycosylation is the oxidation of proteins by glucose resulting in
cross-linking of proteins and which is implicated in loss of cell
function, genome integrity and accelerated aging.
L-Carnosine also protects the aging process of the brain by retarding
lipid peroxidation and stabilizing cell membranes.
Carnosine helpful in Vegetarians and Diabetic Nephropathy
In recent years carnosine has
been getting more respect. This nutrient, made of 2 amino acids, alanine
and histadine, is gradually getting a reputation as a powerful natural
antioxidant. Unfortunately, carnosine is hardly found in a
vegetarian
diet. Hence, those who don't eat meat products may benefit from taking
this nutrient as a supplement. A recent study also points to carnosine
being potentially helpful in diabetic nephropathy (kidney failure) by
preventing damage from high sugar levels. Most carnosine capsules are sold in 500
mg. One option is to take carnosine as a supplement two or three times a
week, in the morning. This nutrient has a mild mood balancing effect.
Another option is to take half a capsule three or four times a week.
Carnosine
studies
Carnosine Helpful in Autism
From the day she was born, Betty seemed
different from other infants. At an age when most infants enjoy interacting with
people and exploring their environment, Betty sat motionless in her crib and
didn't respond to rattles or other toys. It wasn’t too long before Betty was
diagnosed with autism. Unfortunately, modern medicine has little to offer as a
cure for this condition. But supplements may be helpful. Researchers at the
Autism and Epilepsy Specialty Services in Lake Bluff, Illinois, investigated 31
children with autism in an 8-week, double-blinded study to determine if carnosine would result in changes. Carnosine is a natural substance composed of
2 amino acids. It is found in relatively high concentrations in several body
tissues, muscles, and nerve tissue, including the brain. The exact role of
carnosine is not well understood, but studies indicate that this nutrient has
antioxidant potential and may also act as a neurotransmitter (chemical messenger
in the nervous system). The children received 800 mg of carnosine a day and were
compared with a group of children on placebo. After 8 weeks, children given
carnosine showed statistically significant improvements on several tests
including an improvement in vocabulary and recognizing a picture.
Comments: Carnosine, also known as L-carnosine,
is sold in health food stores most commonly in capsules of 500 mg. It would be
worthwhile to try 100 to 200 mg of this nutrient before breakfast and lunch for
a few weeks under a pediatrician’s supervision.
Use of carnosine as a natural anti-senescence drug for human beings.
Wang AM, Ma C, Xie ZH, Shen F.Biochemistry (Mosc) 2000 Jul;65(7):869-71.
Department of Biochemistry, Harbin Medical University, Harbin 150086, PR China.
Carnosine is an endogenous free-radical scavenger. The latest research indicates
that apart from the function of protecting cells from oxidation-induced stress damage,
carnosine appears to be able to extend the lifespan of cultured cells, rejuvenate
senescent cells, inhibit the toxic effects of amyloid peptide (A beta), malondialdehyde,
and hypochlorite to cells, inhibit glycosylation of proteins and protein-DNA and
protein-protein cross-linking, and maintain cellular homeostasis. Also, carnosine seems to
delay the impairment of eyesight with aging, effectively preventing and treating senile
cataract and other age-related diseases. Therefore, carnosine may be applied to human
being as a drug against aging.
Use for cataracts
Babizhayev MA, et al. Efficacy of N-acetylcarnosine in the treatment of cataracts.
Drugs R D 2002;3(2):87-103
Are there concerns taking a full capsule
of carnosine and a full capsule of carnitine together?
It may be better to take half of each rather than a full capsule of
each nutrient.