Ashwagandha extract - Ashwagandha for children
Ashwagandha is a shrub cultivated in India and North America whose roots have been used for thousands of years by Ayurvedic practitioners. Ashwagandha root extract contains flavonoids and many active ingredients of the withanolide class. Several studies over the past few years have indicated that ashwagandha extract has anti-inflammatory, anti-tumor , anti-stress, antioxidant, mind-boosting, immune-enhancing, and rejuvenating properties (see studies at bottom of page). Historically ashwagandha has also been noted to have sex-enhancing properties. Ashwagandha may be used by children at the third of the dosage in the capsule, but only a few times a week with a full week off each month.
Ashwagandha extract 5:1,
mg, 60 veggie caps
Formulated by Ray Sahelian, M.D.
Ashwagandha extract is used as a general tonic and "adaptogen", helping the body adapt to stress. In addition, Ashwagandha extract has been shown to possess antioxidant activity.
Ashwagandha Extract Supplement Facts:
Ashwagandha extract (5:1 extract) - 500 mg - this means it is five times the concentration of the regular ashwagandha herb powder. Suitable for vegetarians.
Suggested Use: As an herbal dietary supplement, take half or 1 Ashwagandha extract capsule a few times a week.
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Antioxidant researchers from Banaras Hindu University in Varanasi, India, have discovered that some of the chemicals within ashwagandha extract are powerful antioxidants. They tested these compounds for their effects on rat brain and found an increase in the levels of three natural antioxidantssuperoxide dismutase, catalase and glutathione peroxidase. They say, "These findings are consistent with the therapeutic use of ashwagandha as an Ayurvedic rasayana (health promoter). The antioxidant effect of active principles of ashwagandha may explain, at least in part, the reported anti-stress, cognition-facilitating, anti-inflammatory and anti-aging effects produced by them in experimental animals, and in clinical situations."
Ashwagandha is used in India to
treat mental deficits in geriatric patients, including amnesia. Researchers from the
University of Leipzig in Germany, wanted to find out which neurotransmitters were
influenced by ashwagandha. After injecting some of the chemicals in ashwagandha into rats,
they later examined slices of their brain and found an increase in acetylcholine receptor
activity.The researchers say, "The drug-induced increase in acetylcholine receptor
capacity might partly explain the cognition-enhancing and memory-improving effects of
extracts from Withania somnifera observed in animals and humans."
A 2002 laboratory study indicates ashwagandha extract stimulates the growth of axons and dendrites. A 2001 study in rodents showed ashwagandha extract had memory boosting ability. A 2000 study with rodents showed ashwagandha to have anti-anxiety and anti-depression effects.
Aphrodisiac Properties of Ashwagandha extract
Ashwagandha is historically used as a sex enhancer. Laboratory studies show it can produce nitric oxide which is known to dilate blood vessels. Ashwagandha is an Ayurvedic herb.
Growth inhibition of human tumor cell lines by withanolides from Withania somnifera (ashwagandha) leaves.
Jayaprakasam B. Michigan State University, East Lansing, MI 48824, USA.
Life Sci. 2003 Nov 21;74(1):125-32.
Ayurvedic medicines prepared in India consist of ashwagandha as one of the main ingredients. Ashwagandha is consumed as a dietary supplement around the world. The leaves of ashwagandha were used in the treatment of tumors and inflammation in several Asian countries. We have isolated twelve withanolides from the leaves of this species. Compounds were tested for their anti-proliferative activity on NCI-H460 (Lung), HCT-116 (Colon), SF-268 (Central Nervous System; CNS and MCF-7 (Breast) human tumor cell lines. Withaferin A and its derivatives exhibited inhibitory concentrations (50%) ranging from 0.24 +/- 0.01 to 11.6 +/- 1.9 microg/mL. Viscosalactone B (12) showed the 50% inhibition at concentrations ranging from 0.32 +/- 0.05 to 0.47 +/- 0.15 microg/mL whereas its 27-O-glucoside derivative (10) exhibited IC50 between 7.9 +/- 2.9 and 17.3 +/- 3.9 microg/ml. Therefore, incorporation of ashwagandha in the diet may prevent or decrease the growth of tumors in human.
Ashwagandha attenuates antioxidant defense in aged spinal
cord and inhibits copper induced lipid peroxidation and protein oxidative
Gupta SK. Department of Zoology, Kurukshetra University, Haryana, India.
Drug Metabol Drug Interact. 2003;19(3):211-22.
We investigated the effects of Ashwagandha on copper-induced lipid peroxidation and antioxidant enzymes in aging spinal cord of Wistar rats. The activity of glutathione peroxidase (GPx) decreased significantly in the spinal cord from adult to aged mice. Treatment with Ashwagandha successfully attenuated GPx activity and inhibited lipid peroxidation in a dose dependent manner. Ashwagandha inhibited both the lipid peroxidation and protein oxidative modification induced by copper. These effects were similar to those of superoxide dismutase and mannitol. The results indicate the therapeutic potential of Ashwagandha in aging and copper-induced pathophysiological conditions.
Ashwagandha supplement pill emails
Q. Can ashwangandha improve eyesight?
A. The influence of ashwagandha on Eyesight is minimal compared to other herbs and supplements such as Lutein.
Q. Is ashwagandha appropriate for children with
anxiety, age 10?
A. If the child's doctor approves, a third of a capsule of the ashwagandha product listed above is worth a try. The capsule can be easily opened by pulling on the ends and mixing the content with an ounce or two of juice.
Q. Your product product is 5:1 extract 500 mg
which I think is pretty good. I am confused however, I came across an
ashwagandha product that states 1.5% 4.5mg extract at 300mg. Yours
is simpler to understand and not forgetting the nice price but what does
the other mean?
A. Ashwagandha herb is available as a regular powder and in various extract potencies. We have come across at least a dozen different extract potencies for this herb with different strengths and different standardization and withanolide percentages. There are no accepted guidelines regarding whether it is preferable to take the whole herb or an extract. If an extract, which is the best form? There are no clear answers to this. The best way to find out is for a consumer to try 2 or 3 different ashwagandha products in varying dosages to see which one works best for them. One person may like a particular product, another person may like another.
Q. I am confused about ashwagandha having
or not having the amino acid arginine. Please send a quick response and
let me know if ashwagandha herb does, or doesn't have arginine in it. I
have been reading a bunch about it and hear that it has high amounts of
arginine and ornithine, which would account for its sex-enhancing
properties ( erectile function). Or do other properties in the herb
enhance things? Ashwagandha sounds like it does the exact same thing to
the male reproductive system as supplemental arginine would or by eating
foods high in the amino acid?
A. The sexual effects of ashwagandha are not due to arginine. If arginine is present in ashwagandha herb it is in the tiniest amounts that are clinically irrelevant. Arginine has dozens of compounds in it that work in many ways in the body and their effects are very different than arginine. It is a distraction to focus on the arginine content or lack thereof in ashwagandha herb.
butea be taken with
A. If the dosages are low, yes.
back to yohimbe bark For additional ashwagandha extract studies information, see Ray Sahelian, M.D.
Q. I started to take it after hearing about it from an individual who was learning Ayurvedic medicine. Started with another brand last summer 2009 with the idea of strengthening the immune system for the winter (long and cold in central Maine!). Probably started a bit early as it generated significant heat. Found the Physician Formula website after conducting an ashwagandha search. Felt Dr Sahelian had researched thoroughly, was open about the source of supply and, I guessed, would have a knowledge of Ayurvedic medicine. I am unsure whether it has strengthened my immune system but as the herb has anti oxidant and anti stress/anxiety properties I plan to continue using it and have changed my source of supply to Physician Formula. There is a possibility the herb has enabled me to be more accepting of life's situations. My current thinking is to stop the ashwagandha during our warm and hot months of May to September.
ashwagandha extract for sexual enhancement, see tongkat ali website or yohimbe article.
more ashwagandha information