Ashwagandha extract use for relaxation and for children,
what is the right dosage to take and what time of day should you take it
March 7 2014
Ashwagandha is a shrub cultivated in India and North America whose roots have been used for thousands of years by Ayurvedic practitioners. Ashwagandha root extract contains flavonoids and many active ingredients of the withanolide class. Several studies over the past few years have indicated that ashwagandha extract has anti-inflammatory, anti-tumor , anti-stress, antioxidant, mind-boosting, immune-enhancing, and rejuvenating properties (see studies at bottom of page). Historically ashwagandha has also been noted to have sex-enhancing properties. Ashwagandha may be used by children at the third of the dosage in the capsule, but only a few times a week with a full week off each month.
mg, 60 veggie caps
Formulated by medical doctor Ray Sahelian, M.D.
Ashwagandha extract is used as a general tonic and "adaptogen", helping the body adapt to stress. In addition, it has been shown to possess antioxidant activity.
Ashwagandha extract (5:1 extract) - 500 mg - this means it is five times the concentration of the regular herb powder. Suitable for vegetarians.
Suggested Use: As an herbal dietary supplement, take half or 1 Ashwagandha extract capsule a few times a week.
buy Ashwagandha extract, Passion Rx, Mind Power Rx
Ashwagandha benefits and which medical conditions to use this herb
Investigators at Banaras Hindu University in Varanasi, India, have discovered that some of the chemicals within ashwagandha extract are powerful antioxidants. They tested these compounds for their effects on rat brain and found an increase in the levels of three natural antioxidantssuperoxide dismutase, catalase and glutathione peroxidase. They say, "These findings are consistent with the therapeutic use of ashwagandha as an Ayurvedic rasayana (health promoter). The antioxidant effect of active principles of ashwagandha may explain, at least in part, the reported anti-stress, cognition-facilitating, anti-inflammatory and anti-aging effects produced by them in experimental animals, and in clinical situations."
Ashwagandha is used in India to treat mental deficits in geriatric patients, including amnesia. Researchers from the University of Leipzig in Germany, wanted to find out which neurotransmitters were influenced by ashwagandha. After injecting some of the chemicals in ashwagandha into rats, they later examined slices of their brain and found an increase in acetylcholine receptor activity.The researchers say, "The drug-induced increase in acetylcholine receptor capacity might partly explain the cognition-enhancing and memory-improving effects of extracts from Withania somnifera observed in animals and humans."
A 2002 laboratory study indicates ashwagandha extract stimulates the growth of axons and dendrites. A 2001 study in rodents showed ashwagandha extract had memory boosting ability. A 2000 study with rodents showed ashwagandha to have anti-anxiety and anti-depression effects.
Aphrodisiac Properties of Ashwagandha extract, an Ayurvedic herb
Ashwagandha is historically used as a sex enhancer. Laboratory studies show it can produce nitric oxide which is known to dilate blood vessels.
Ashwagandha and children,
use by a child
Parents may give it to children as long as it is used at most three times a week and the dosage is a third or half of the adult dose.
Q. Is ashwagandha supplement pill appropriate for children with
anxiety, age 10?
A. If the child's doctor approves, a third of a capsule of the product listed above is worth a try. The capsule can be easily opened by pulling on the ends and mixing the content with an ounce or two of juice.
Growth inhibition of human tumor cell lines by withanolides from Withania somnifera (ashwagandha) leaves.
Michigan State University, East Lansing, MI, USA. Life Sci. 2003.
Ayurvedic medicines prepared in India consist of ashwagandha as one of the main ingredients. Ashwagandha is consumed as a dietary supplement around the world. The leaves of ashwagandha were used in the treatment of tumors and inflammation in several Asian countries. We have isolated twelve withanolides from the leaves of this species. Compounds were tested for their anti-proliferative activity on NCI-H460 (Lung), HCT-116 (Colon), SF-268 (Central Nervous System; CNS and MCF-7 (Breast) human tumor cell lines. Withaferin A and its derivatives exhibited inhibitory concentrations (50%) ranging from 0.24 to 11 microg/mL. Viscosalactone B (12) showed the 50% inhibition at concentrations ranging from 0.32 to 0.47 microg/mL. Therefore, incorporation of ashwagandha in the diet may prevent or decrease the growth of tumors in human.
Ashwagandha attenuates antioxidant defense in aged spinal
cord and inhibits copper induced lipid peroxidation and protein oxidative
Department of Zoology, Kurukshetra University, Haryana, India. Drug Metabol Drug Interact. 2003.
We investigated the effects of Ashwagandha on copper-induced lipid peroxidation and antioxidant enzymes in aging spinal cord of Wistar rats. The activity of glutathione peroxidase (GPx) decreased significantly in the spinal cord from adult to aged mice. Treatment with Ashwagandha successfully attenuated GPx activity and inhibited lipid peroxidation in a dose dependent manner. Ashwagandha inhibited both the lipid peroxidation and protein oxidative modification induced by copper. These effects were similar to those of superoxide dismutase and mannitol. The results indicate the therapeutic potential of Ashwagandha in aging and copper-induced pathophysiological conditions.
Q. Your product product is 5:1 extract 500 mg which I think is pretty good. I am confused however, I came across an ashwagandha product that states 1.5% 4.5mg extract at 300mg. Yours is simpler to understand and not forgetting the nice price but what does the other mean?
A. Ashwagandha herb is available as a regular powder and in various extract potencies. We have come across at least a dozen different extract potencies for this herb with different strengths and different standardization and withanolide percentages. There are no accepted guidelines regarding whether it is preferable to take the whole herb or an extract. If an extract, which is the best form? There are no clear answers to this. The best way to find out is for a consumer to try 2 or 3 different ashwagandha products in varying dosages to see which one works best for them. One person may like a particular product, another person may like another.
I am confused about ashwagandha having
or not having the amino acid arginine. Please send a quick response and
let me know if ashwagandha herb does, or doesn't have arginine in it. I
have been reading a bunch about it and hear that it has high amounts of
arginine and ornithine, which would account for its sex-enhancing
properties ( erectile function). Or do other properties in the herb
enhance things? Ashwagandha sounds like it does the exact same thing to
the male reproductive system as supplemental arginine would or by eating
foods high in the amino acid?
The sexual effects of ashwagandha are not due to arginine. If arginine is present in the herb it is in the tiniest amounts that are clinically irrelevant. Arginine has dozens of compounds in it that work in many ways in the body and their effects are very different than arginine. It is a distraction to focus on the arginine content or lack thereof in ashwagandha herb.
Can butea be taken with
If the dosages are low, yes.
Which is more potent, ashwagandha or yohimbe bark in terms of their aphrodisiac effects?
Yohimbe is more potent.
I started to take it after hearing about it from an individual who was learning Ayurvedic medicine. Started with another brand last summer 2009 with the idea of strengthening the immune system for the winter (long and cold in central Maine!). Probably started a bit early as it generated significant heat. Found the Physician Formula website after conducting an ashwagandha search. Felt Dr Sahelian had researched thoroughly, was open about the source of supply and, I guessed, would have a knowledge of Ayurvedic medicine. I am unsure whether it has strengthened my immune system but as the herb has anti oxidant and anti stress/anxiety properties I plan to continue using it and have changed my source of supply to Physician Formula. There is a possibility the herb has enabled me to be more accepting of life's situations. My current thinking is to stop the ashwagandha during our warm and hot months of May to September.
My wife uses ashwagandha Indian herb for Parkinson's
disease made by Medi-Herb and distributed by Standard Process. It is pharm grade
and is only sold to health professionals. My daughter is a VET, so I had her
register and ordered thru her. There is a Canadian outfit called Promedics, that
markets it from British Columbia. She takes one teaspoon in H20 or juice, has
been taken it now for about a month;- with the benefits she felt after 2 weeks,
MORE ENERGY; Her mobility has improved a lot....walking better, more active BETTER appetite: She eats and drinks very good, even if most of the foods have to be soft, as she cannot chew her food too well. Has gained 5lbs! Was very low before at 99 lbs. HAS IMPROVED HER BLOOD Pressure! Even if she is hypertensive, her BP is now much better regulated, less highs and less real lows (Hypotensive). It tastes terrible, being a bitter herb, but she gulps it down, as she knows it does her good. It costs $43.95 for 200ml, or $93 Canadian dollars for 500ml. She also takes 3 sinemet (25/100) per day + 1 CR before retiring.
Iíve used ashwagandha from a reputable herb shop in the
city. It had a distinct smell and flavor. The flavor was similar to maca, both
are unique. It was a fine powder with a beige color. It had distinct relaxing
effects. Recently I tried a source for ashwagandha from the internet. The
company distributing it is 1Fast400. They call it ashwagandha 5%. Apparently
they mean 5% withanolides. This ashwagandha 5% smells, tastes and appears very
different. Even at a 5% concentration it should not appear, smell and taste as
different as it does. The 5% version smells, tastes and looks like fine ground
freeze dried coffee. Itís very dark and abundant with sparkling facets just like
freeze dried coffee. It dissolves instantly on contact with water. None of these
qualities and characteristics are found with the strait powdered ashwagandha
which does not mix easily in water and certainly does not dissolve at all. Also
the effect of the 5% version acts like a stimulant. Iím rather concerned that
this company is distributing an unknown substance under the name ashwagandha. Is
there any way to test this 5% version to confirm what it really is?
There is a way to test and it costs about 250 dollars for a HPLC test at a scientific laboratory that does such testing. The same herb, from different manufacturers, could have different colors based on a number of factors including the original plant, harvesting, use of stems, leaves or bark, how it is processed, etc.
I am tapering off prozac, currently down to 3 mgs per
day. Can I start taking the Ashwagandha now?
This is a decision you and your doctor need to make.