Arjuna
terminalia arjuna information and product
Ancient Indian Medical knowledge known as Ayurveda
goes back millennia. The Vedas and Puranas refer various materials of medical
importance including herbs, plants and trees, etc. Ancient medical scientists
have mentioned the properties of Arjuna. Modern research has discovered that
Arjuna has antioxidant properties and may be clinically helpful in patients with
angina. For an excellent
multivitamin product.
Arjuna, 550 mg,
Planetary Formulas

Arjuna Supplement
Facts
Serving Size 1 Tablet
Servings per bottle: 120
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Terminalia arjuna Bark -
500 mg
Terminalia arjuna Bark Extract -
50 mg
(standardized 10:1 extract)
Suggested use: Take one Arjuna tablet once a day or as recommended by your health care provider.
High Quality products formulated by a
medical doctor


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Arjuna and the Heart
Arjuna is helpful in patients with angina (see study below)
Arjunolic acid, a new triterpene and a potent principle from the bark of
Terminalia arjuna, has been shown to provide significant cardiac protection in
isoproterenol induced myocardial necrosis in rats. Arjunolic acid treatment
prevents the decrease in the levels of superoxide dismutase, catalase,
glutathione peroxidase, ceruloplasmin, alpha-tocopherol, reduced glutathione (GSH),
ascorbic acid, lipid peroxide, MPO and the cardioprotection is confirmed by the
histopathological studies. This study shows that the cardioprotection of
arjunolic acid pre and post treatment could possibly be due to the protective
effect against the damage caused by myocardial necrosis.
Additional benefits of Arjuna
Arjuna bark has inotropic and hypotensive effects, increase coronary artery flow
and protecs myocardium against ischemic damage. Arjuna also has mild diuretic,
blood thinning properties. There is clinical evidence of its beneficial effect
in coronary artery disease alone and along with statin.
Arjuna has compounds that help protect against DNA damage from toxins.
Compounds in Arjuna lower cholesterol and have antioxidant properties.
Compounds found in Arjuna
A triterpene glycoside, arjunetoside, together with oleanolic and
arjunic acids, and a cardenolide, have been isolated from the root bark of
Terminalia arjuna. Cytotoxic agents in arjuna herb include arjunic acid,
arjungenin, arjunetin and arjunoglucoside.
Arjuna
studies
Antimutagenic activities of acetone and methanol fractions of Terminalia arjuna.
Kaur K. Guru Nanak Dev University, Amritsar, India.
kamal_Food Chem Toxicol. 2002 Oct;40(10):1475-82.
The antimutagenic effect of benzene, chloroform, acetone and methanol
fractions from Terminalia arjuna, a well-known medicinal plant, was determined
against Acid Black dye, 2-aminofluorene (2AF) and 4-nitro-o-phenylenediamine (NPD)
in TA98 Frameshift mutagen tester strain of Salmonella typhimurium. Among the
different fractions, the antimutagenic effect of acetone and methanol fractions
was more than that observed with other fractions. Co-incubation and
pre-incubation modes of experimentation did not show much difference in the
antimutagenic activity of the extracts. Moreover, these fractions inhibited the
S9-dependent mutagens, 2AF and Acid Black dye more effectively than the
direct-acting mutagens. Studies are under way to isolate and elucidate the
nature of the antimutagenic factor in acetone and methanol fractions of arjuna.
Efficacy of Terminalia arjuna in chronic stable angina: a
double-blind, placebo-controlled, crossover study comparing Terminalia arjuna
with isosorbide mononitrate.
Bharani A. MGM Medical College and MY Hospital,
Indore, MP. Indian Heart J. 2002 Mar-Apr;54(2):170-5.
Terminalia arjuna, an Indian medicinal plant, has been reported to
have beneficial effects in patients with ischemic heart disease in a number of
small, open studies. The need for a double-blind, randomized, placebo-controlled
study with adequate sample size has long been felt. The arjuna bark extract
contains acids (arjunic acid, terminic acid), glycosides (arjunetin arjunosides),
strong antioxidants (flavones, tannins, oligomeric proanthocyanidins), minerals.
etc. and exhibits anti-ischemic properties. Fifty-eight
males with chronic stable angina (NYHA class II-III) with evidence of provocable
ischemia on treadmill exercise test received Terminalia arjuna (500 mg 8
hourly), isosorbide mononitrate (40 mg/daily) or a matching placebo for one week
each, separated by a wash-out period of at least three days in a randomized,
double-blind, crossover design. They underwent clinical, biochemical and
treadmill exercise evaluation at the end of each therapy which were compared
during the three therapy periods. Terminalia arjuna therapy was associated with
significant decrease in the frequency of angina and need for isosorbide
dinitrate. The treadmill exercise test parameters improved significantly during
therapy with Terminalia arjuna compared to those with placebo. The total
duration of exercise increased, maximal ST depression during the longest
equivalent stages of submaximal exercise decreased , time to recovery decreased,
and higher double products were achieved during Terminalia arjuna therapy.
Similar improvements in clinical and treadmill exercise test parameters were
observed with isosorbide mononitrate compared to placebo therapy. No significant
differences were observed in clinical or treadmill exercise test parameters when
Terminalia arjuna and isosorbide mononitrate therapies were compared. No
significant untoward effects were reported during Terminalia arjuna therapy.
Terminalia arjuna bark extract, 500 mg 8 hourly, given to patients
with stable angina with provocable ischemia on treadmill exercise, led to
improvement in clinical and treadmill exercise parameters as compared to placebo
therapy. These benefits were similar to those observed with isosorbide
mononitrate (40 mg/day) therapy and the extract was well tolerated. Limitations
of this study include applicability of the results to only men with chronic
stable angina but not necessarily to women, as they were not studied.
Arjuna supplements questions
Q. I take two capsules of arjuna bark powder every day, to strengthen my heart.
I also have osteoarthritis so I started a new "arthrozyme" tablet, with which I
cannot take any blood thinning medications. I wanted to know that does arjuna
has any blood thinning properties.
A. Arjuna has mild blood thinning activity.
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arjuna studies