Acetyl-l carnitine Supplement product
Acetyl-l carnitine pill health
benefit and review of
L-carnitine L-tartrate
supplements and various types of this dietary supplement
Benefit of for sexual
enhancement and a review of side effects
Acetyl-l carnitine is a stabilized form of the amino acid metabolite L Carnitine and is utilized in the same manner in the body. ALCAR plays an important role in protecting and supporting brain function. I may also be useful in sexual energy enhancement.
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Acetyl-l carnitine Supplement product
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Benefit of acetyl-l carnitine
product
The mind boosting effect of acetyl-l carnitine is often noticed within a
few hours, or even within an hour. Most people report feeling mentally sharper,
having more focus and being more alert. Some find a mild mood enhancement.
acetyl-l carnitine may be used as an overall mind booster. The typical dosage is 250 mg
once a day or a few times a week.
Additional benefit of
acetyl-l carnitine
This nutrient may be helpful in those with Alzheimer's disease or have a form of
fertility problem where acetyl-l carnitine could be useful.
Acetyl-L-Carnitine and Diabetic Neuropathy
An evaluation from two 52-week randomized placebo-controlled
clinical diabetic neuropathy trials testing acetyl-l-carnitine demonstrated that
acetyl-l-carnitine treatment is beneficial in alleviating symptoms (particularly pain) and improves nerve fiber regeneration and vibration
perception in patients with established diabetic neuropathy. The study was
published in Diabetes Care journal.
Acetyl-l-Carnitine versus testosterone for sexual
enhancement, mood and energy
Can acetyl-l-carnitine, a natural nutrient, be just as good for aging men
as testosterone? In this Italian study, a total of 120 men (age range 60
to 74) were randomized into three groups. Group 1 was given testosterone,
the second group was given propionyl-L-carnitine 2 grams a day plus
acetyl-L-carnitine 2 grams a day. The third group was given a placebo. Testosterone, carnitines and placebo were given for 6 months.
Testosterone and carnitines significantly improved performance on
several tests that measure sexual function, mood, and energy. These tests
included nocturnal penile tumescence, Depression Melancholia Scale score, and fatigue scale
score. Carnitines proved significantly more active than testosterone in
improving sexual function. Testosterone significantly increased the prostate volume
and testosterone levels; carnitines did not. Carnitines and
testosterone proved effective for as long as they were administered. No
major side effects were reported within the 6 month study period.
Nerve regeneration influence
Effect of Acetyl-L-Carnitine on Axonal Sprouting Following Donor Nerve
Injury Distal to an End-to-Side Neurorrhaphy Model.
J Reconstr Microsurg. 2009 Aug 20. Kokkalis ZT, Soucacos PN, Terzis
JK. International Institute of Reconstructive Microsurgery, Eastern
Virginia Medical School, Norfolk, Virginia.
This study investigated the hypothesis that acetyl-L-carnitine (ALCAR)
could have a significant effect on nerve regeneration after end-to-side
neurorrhaphy. The ability of the ALCAR to enhance nerve regeneration in
combination with various types of donor nerve injury distal to the
coaptation site was also determined. Twenty-five Sprague-Dawley rats
were randomized to five groups of five animals each, in which three
different types of donor injury (crush, ligation, and transection
injury) distal to the coaptation site were executed (groups C, D, and E,
respectively). Animals in group A (placebo) and group B underwent a
standard end-to-side neurorrhaphy. Animals from groups B to E received a
daily intraperitoneal injection of 50 mg/kg/d of ALCAR, and a placebo
was injected in place of ALCAR in animals in group A. Administration of
acetyl-L-carnitine alone did not prove to be a significant stimulus for
regeneration, as concluded after comparison among the two noninjury
models of the donor nerve (groups A and B). Indeed, the combination of
an injury model of the donor nerve (crush injury) with administration of
acetyl-L-carnitine proved to be a significantly more potent stimulus for
regeneration than the control (placebo) group, as measured by
behavioral, muscle morphometric, electrophysiological, and
histomorphometric studies.
Acetyl-l
carnitine side effect, safety
Side effects of acetyl-l carnitine include overstimulation at dosages greater
than 500 mg. Nausea is another acetyl-l carnitine side effect.
Other acetyl-l carnitine products
available over the counter
Acetyl-l carnitine, 250 mg,
Source Naturals
Acetyl-l carnitine, 500 mg,
Now Foods
Acetyl-l-Carnitine
and testosterone for sexual health, mood and energy
Can acetyl-l-carnitine, a natural nutrient, be just as good for aging men
as testosterone? In this Italian study, a total of 120 men (age range 60
to 74) were randomized into three groups. Group 1 was given testosterone,
the second group was given propionyl-l-carnitine 2 grams a day plus
acetyl-l-carnitine 2 grams a day. The third group was given a placebo. Testosterone, carnitines and placebo were given for 6 months.
Testosterone and acetyl-l-carnitine along with propionyl-l-carnitine improved performance on
several tests that measure sexual function, mood, and energy. These tests
included nocturnal penile tumescence, Depression Melancholia Scale score, and fatigue scale
score. Acetyl-l-carnitine and propionyl-l-carnitine proved significantly more active than testosterone in
improving sexual function. Testosterone significantly increased the prostate volume
and testosterone levels; Acetyl-l-carnitine and propionyl-l-carnitine did not.
Comment: Acetyl-l-carnitine and propionyl-l-carnitine appeared to be
slightly more effective and safer than testosterone.
Q. I understand ALC can be useful for sexual energy
improvement, what about tongkat ali
herb or
yohimbe bark
extract, are they helpful, too?
A. Certainly. These herbs are very potent and effective for this
purpose.
Acetyl-lcarnitine beneficial
for macular degeneration
Improvement of visual functions and fundus alterations in early
age-related macular degeneration treated with a combination of acetyl-L-carnitine,
n-3 fatty acids, and coenzyme Q10.
Ophthalmologica. 2005 May-Jun;219(3):154-66. Ophthalmic Neuroscience
Program, Department of Ophthalmology, University of Rome 'La Sapienza',
Rome, Italy.
The aim of this randomized, double-blind, placebo-controlled clinical
trial was to determine the efficacy of a combination of acetyl-L-carnitine,
n-3 fatty acids, and coenzyme Q10 (Phototrop) on the visual functions and
fundus alterations in early age-related macular degeneration (AMD). One
hundred and six patients with a clinical diagnosis of early AMD were
randomized to the treated or control groups. The primary efficacy variable
was the change in the visual field mean defect (VFMD) from baseline to 12
months of treatment, with secondary efficacy parameters: visual acuity (Snellen
chart and ETDRS chart), foveal sensitivity as measured by perimetry, and
fundus alterations as evaluated according to the criteria of the
International Classification and Grading System for AMD. The mean change
in all four parameters of visual functions showed significant improvement
in the treated group by the end of the study period. Decrease in drusen-covered
area of treated eyes was also statistically significant as compared to
placebo. These findings strongly suggested that an appropriate combination
of compounds which affect mitochondrial lipid metabolism, may improve and
subsequently stabilize visual functions, and it may also improve fundus
alterations in patients affected by early AMD.
L-carnitine L-tartrate
supplements
The effects of L-carnitine L-tartrate supplementation on hormonal
responses to resistance exercise and recovery.
Kraemer WJ. University of
Connecticut, Storrs, CT 06269, USA.
J Strength Cond Res. 2003 Aug;17(3):455-62.
The purpose of this investigation was to examine the influence of L-carnitine L-tartrate supplementation using a balanced, cross-over, placebo-controlled research
design on the anabolic hormone response (i.e., testosterone [T], insulin-like
growth factor-I, insulin-like growth factor-binding protein-3 [IGFBP-3], and immunofunctional and immunoreactive growth hormone [GHif and GHir]) to acute
resistance exercise. Ten healthy, recreationally weight-trained men
volunteered and were matched, and after 3 weeks of supplementation (2 g carnitine per
day), fasting morning blood samples were obtained on six consecutive days
(D1-D6). Subjects performed a squat protocol (5 sets of 15-20 repetitions) on
D2. During the squat protocol, blood samples were obtained before exercise and
0, 15, 30, 120, and 180 minutes postexercise. After a 1-week washout period,
subjects consumed the other supplement for a 3-week period, and the same
experimental protocol was repeated using the exact same procedures. Expected
exercise-induced increases in all of the hormones were observed for GHir, GHif,
IGFBP-3, and T. Over the recovery period, carnitine reduced the amount of
exercise-induced muscle tissue damage, which was assessed via magnetic resonance
imaging scans of the thigh. carnitine supplementation significantly
increased IGFBP-3 concentrations prior to and at 30, 120, and 180 minutes after
acute exercise. No other direct effects of carnitine supplementation were observed on
the absolute concentrations of the hormones examined, but with more undamaged
tissue, a greater number of intact receptors would be available for hormonal
interactions. These data support the use of carnitine as a recovery supplement for
hypoxic exercise and lend further insights into the hormonal mechanisms that may
help to mediate quicker recovery.
Acetyl-l Carnitine pill questions
What is
acetyl-l carnitine arginate?
We are not familiar with
acetyl- l carnitine arginate pills.
Q. Is headache a l acetyl-l carnitine side effect?
A. In a few people, headache may be a cause of a high dose of
l acetyl- l carnitine side effect.
Q. Can you please explain to me in a simple way. I
don't have a lot of knowledge in medicine or chemical terminology. What is
the difference between the l-carnitine and the acetyl l carnithine? Are
they the same thing? If different from each other, how that difference
affects any person taking those products? Can they be taken in a
combination or make no difference either one you take? Because they are
two names for something, that looks to me like the same product; I'm kind
of confused. Basically; I know, that there is a difference on price
between these two products for whatever reason, but that's all I know.
A. Acetyl carnitine (also
spelled as acetyl l carnitine or acetyl-l carnitine) and carnitine play several
important roles in the human body. These nutrients shuttle acetyl groups and fatty acids
into mitochondria for energy production. Without carnitine, fatty acids cannot easily
enter into mitochondria. The acetyl group of acetyl l carnitine is used to form
acetyl-CoA, the most important intermediary in the generation of energy from
amino acids, fats, and carbohydrates. Therefore, acetyl l carnitine serves as an
energy reservoir of acetyl groups and both acetylcarnitine and carnitine help
improve energy production. The acetyl group of acetyl l carnitine is also used to make the important brain chemical
acetylcholine. Some studies suggest that perhaps acetyl l carnitine can even act as a neurotransmitter itself. Those who take carnitine pills notice an increase in physical energy, but
not as much mental energy. Acetyl l carnitine has a significantly more
immediate and noticeable mental effect than carnitine because it crosses into
the brain much better. The mind boosting effect of acetyl l carnitine is often noticed within a few
hours, or even within an hour. Most people report feeling mentally sharper,
having more focus and being more alert. Some find a mild mood enhancement.
Is it too high a dose to combine coq10 100
mg with acetyl l carnitine 500 mg?
For most people, yes. We suggest limiting it to
CoQ10 30mg and acetyl l carnitine to 300 mg
or less.
I have read that individuals with thyroid
disease should avoid taking the alc and ala supplement but the
information does not state what the side effect is. I am 75 yrs old,
have taken the supplement 500mg ALC and ALA 200mg combo w/breakfast) for
more than 10 yrs without any apparent side effect that I am aware of. I
am in good health and very active. I also take 75 mcg levothyroid daily
when awakening for hypothyroidism. What is your advice regarding this
alc / ala supplement?
We prefer to use lower dosages but different doctors have
different opinions.
Can this mind enhancer be taken with other
herbs that have an influence on memory and alertness such as
bacopa monnieri?
Probably but we suggest you try each separately and if you
combine them, use lower dosages of bacopa monnieri.